For thousands of years folk medicine has utilized mushrooms
for medicinal purposes. Chinese have practiced for centuries that mushrooms promote a healthy and long
life. There is even evidence
within the Egyptian hieroglyphs that Egyptians prized mushrooms, generally
reserving them as a food of royalty and associating them with immortality. Today, modern medicine and science
continue to find evidence that traditional healers seemed to know what they
were doing. Not only do modern naturopathic
practitioners continue to preach the use of myriad fungi to treat ailments
ranging from inflammation to treatment of the common cold, but Western medicine
is making room for medicinal mushrooms as well.
Coriolus versicolor
(also known as Trametes versicolor)
is more commonly known as the turkey tail mushroom. This mushroom, named for its resemblance to the tail of a
turkey as seen above, has been studied in conjunction to other
more common cancer treatments, including chemotherapy and radiation. Turkey tail mushrooms have been known
to boost immune function and the findings of its use in cancer treatment are
quite promising.
Japan
and China have both isolated extracts from this mushroom (known as PSP and PSK)
and they are often prescribed in these countries as adjunctive treatment for
cancer to boost immune function before, after and during other treatments such
as surgery, chemo and radiation. A
ten-year study in Japan found that Stage I and Stage II patients with non-small
cell carcinoma of the lung who were treated with Coriolus extract had a 39%
5-year survival rate compared to the 16% seen in patients who did not receive
the extract. For Stage III
patients, those treated with extract had a 5-year survival rate of 16% compared
to only 5% seen in the group who did not receive the extract. This data, which was even presented at
the 2009 International Society of Integrative Medicine meeting on IntegrativeOncology for Clinicians and Cancer Patients, provides a new avenue to explore
for boosting immune function in cancer patients. These studies found that the effects of turkey tail
mushrooms occurred at a dose-response rate. This means that as the dose of turkey tail mushrooms, which
come in capsule form, increased, so does immune function.
This next
mushroom provided the derivative for a new medication that is predicted to be
in the top ten most profitable commercially produced drugs in history. The mushroom is Cordyceps sinensis and the drug is Gilenya,
the first oral medication approved to treat multiple sclerosis (MS).
MRI scans of MS patient showing visible lesions |
Cordyceps sinensis sprouting from a caterpillars head |
This mushroom
initially attracted the attention of biologist Tetsuro Fujita because he wanted
to explore the fungus’ mechanism of suppressing the immune system of its
host. Fujita was researching ways
to reduce the chance of rejection of transplant organs by suppressing the
immune systems of patients. In an
interview he even admits that at the time of this discovery, he knew little to
nothing about MS as a disease.
However, it was Fujita’s research at Kyoto University that allowed Japanese drug
researcher Mitsubishi Tanabe to develop a drug that is expected to be worth
more than $5 billion dollars annually by 2018.
Although mushrooms have been a part of folk medicine for
thousands of years, it is clear that it is about time that modern medicine
took the time to look at the ways of tradition.
Not only do mushrooms have the potential for many drug avenues, but
research in other areas show their promise in other ways for disease
control. Check out this video below
presented by Paul Stamets at the 2011 TedMed Conference about the power of
mushrooms for drugs but also as potential for vector control of insects such as mosquitoes and flies, which could have serious implications for diseases such as malaria:
Jae Rhim Lee has also discovered a novel use for mushrooms. Our bodies intake and filter many toxic substances that we encounter on a daily basis. While this makes many concerned for their daily health, Rhim asks us to consider the effects that these toxins that are stored in our bodies will have on the planet when we die. Not only does the decomposition of our bodies allow these toxins to leach into the environment, but the chemicals that we use to slow decomposition and the cosmetics that we use to try and make the dead appear at peace also leach into the environment. Rhim has found a way to utilize edible mushrooms to decompose our bodies when we pass to filter out these toxins before they reach the soil. To learn more about a new potential relationship between your body and your food and a way to return your body to the earth in a greener and more environmentally friendly manner, watch the following TedTalk:
Sources Cited:
Matsuyama, Kanoko (2011). From Soup to MS drug: One Fungus' Journey's. Bloomberg Business Week.
Schachter, Michael (2009). Integrative Oncology for Clinicians and Cancer Patients. INTERNATIONAL JOURNAL OF INTEGRATIVE MEDICINE 2(1): 52 - 92
Images (in order of appearance):
http://jnnp.bmj.com/content/76/suppl_3/iii11.ful
http://humanflowerproject.com/index.php/weblog/comments/an_incursion_for_power_fungus/
Videos (in order of appearance):
http://www.youtube.com/watch?v=XuKjBIBBAL8
http://www.tedmed.com/videos-info?name=Paul_Stamets_at_TEDMED_2011&q=updated&year=all&sid=155&vid=209
http://www.ted.com/talks/jae_rhim_lee.html
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