Sunday, March 4, 2012

From the Bed to the Streets: A Look Into The Human Papillomavirus


Click image for source
 I often come across beautiful animated renditions of various viral pathogens, with their symmetrical shape, rounded features, and overall elegance of design, I almost always forget the power of such small substances. The Human Papillomavirus (HPV, seen above) is an example of a virus most of us would probably not suspect to cause such wide spread harm. Unlike the common flu, or even HIV, HPV often slips under people’s health conscious radar. Even though it falls under the category of sexually transmitted infection (STI), there are many aspects about its virology, transmission, and prevention that makes it a unique contribution to the world of STI’s. As I dig deeper into data surrounding HPV, the more impressed I become at the level of destruction achieved by something so small and relatively simple.        

Falling in the family Papillomaviridae, HPV is a nonenveloped, double-stranded DNA virus. Isolates of HPV are classified as "types," each designated on the basis of the nucleotide sequence of specific regions of the genome. All HPVs have an 8 kilo-base circular genome enclosed in a capsid shell composed of the major and minor capsid proteins L1 and L2 (depicted in the picture above by star-shaped structures budding from the surface). Purified L1 protein will self-assemble to form virus-like particles (VLPs) which are used in vaccines to trigger antibody production in the recipient.

In addition to the structural genes, the genome encodes several early genes (E1, E2, E4, E5, E6, and E7) that enable viral transcription and replication, allowing interaction with the host genome. E6 and E7 proteins are the primary contributors of cancer; they manipulate cell cycle regulators, induce chromosomal abnormalities, and block apoptosis. HPV obviously comes equipped with the tools necessary to complete the job of proper infection; all it needs is a site of entry into a host so one can witness its drastic health effects.
   
HPV enters the body through micro-abrasions that expose areas of the basement membrane. This disturbed epithelial barrier is typical during sexual intercourse or after minor skin abrasions. Interestingly, the use of condoms does not fully protect against infection, as the virus can be spread through contact by other genital areas not covered. It can also be spread through oral sex. 

Once inside, the infection is limited to the stratified epithelium, as this is the only tissue within which it can replicate. Being isolated to this area allows it to be shielded from much of the body’s immune response. HPV lesions are thought to arise from the proliferation of infected basal keratinocyte (the predominate cell type in the epidermis). The circular, double stranded DNA is transported into the nucleus of these cells and by using host replication machinery; HPV establishes itself at a copy number between 10-200 viral genomes per cell. It takes about 12-24 hours for the virus to even initiate transcription, however; after this period it can proliferate uncontrollably.

Once an HPV viron invades a cell, an active infection occurs, and the virus can be transmitted. Several months to years may elapse before it can be clinically detected. I am sure by now the reader is asking, "Sure the biology behind the virus is interesting, but why should I care?" To answer this question, we can take a look at the various detrimental health effects associated with infection.

HPV is a lovely package of afflictions that comes complete with genital warts and a myriad of cancers that can affect numerous areas of the body. While genital warts only represent 1% of the active population, cancers such as, penile, throat, colorectal, and tonsil represent 10,000 cases each year in the U. S. The effect on women is even more severe. HPV is actually the number one cause of cervical cancer, killing 4000 women each year. Just knowing these quick facts allows one to realize how dangerous HPV actually is and it only gets worse when you consider its prevalence in the population.

It is the most common STI in the U.S. According to the Center for Disease Control and Prevention (CDC), 45% of college aged woman are currently infected. There are currently 20 million people infected in the U.S. with 6 million new infections annually. Most HPV infections are asymptomatic or simply unrecognized with 90% of people able to clear infection within two years. Put in another way, about half of sexually active people will contract HPV some point in their lives.

According to the CDC there are around 120 different types. Around 30-40 of those are actually associated with sexual transmission. Of these there are what are considered to be high-risk and low risk types. High-risk includes cancer causing types and low-risk includes wart causing types (see below). Interestingly, a viral type cannot cause both; it is either wart or cancer causing. Given all of this information, it is imperative to have a means of prevention in order to thwart possible infection.

Click on image for source: Low-risk genital warts
Click on image for source: High-risk cervical cancer


Of two vaccines that are currently on the market today, the most popular is the quadrivalent vaccine, Gardasil, which contains HPV types 11, 6, 18, and 16. These represent four of the most common types, with 16 and 18 representing 70% of cervical cancers, 11 and 6 representing 90% of genital warts. The other vaccine, Cervarix, is a bivalent vaccine containing types 16 and 18 only. Currently, either vaccine can be administered to women ages 9-26 with an efficacy close to 100%. As of the October of 2011, the Gardasil vaccine has also been approved for men between 9-26 years of age. For either gender, administration of the vaccine before the onset of sexual maturity is optimal. Introducing the vaccine into a young immune system gives the body the ability to produce sufficient levels of antibodies against these four main types. This protection of course, comes at a price. 

Click on image for source
Both of the vaccines are administered in a 3 dose series over a 6 month period with each does costing $120. The total $360 does not give you fool proof protection. Remember, this vaccine only covers the four main types and significant time needs to pass before your body produces sufficient levels of antibodies to fight any sort of exposure. Women who have received an HPV vaccine should continue routine cervical cancer screening as 30% of cervical cancers are caused by HPV types other than 16 or 18. For anyone interested in getting the vaccine, it is important to know that it does not eliminate the need to have regular cervical screens and will not help cure a current infection.  

More recently, the use of the HPV vaccine has been under political debate. Following its introduction in 2006, Gardasil has been proposed as a possible mandatory vaccine. In 2007 Texas Governor Rick Perry aimed to pass an executive order that would mandate the vaccination for all young girls in Texas. The bill was met with much opposition and, even though it did not pass, the idea of an HPV vaccine mandate still lingers.

The Advisory Committee on Immunization Practices(ACIP) put forth their recommendation for the use of an HPV vaccine by taking into account much of the information discussed in this article. ACIP models have suggested that vaccination of an entire cohort of females aged 12 years could reduce the lifetime risk for cervical cancer by 20%-66%, depending on the efficacy of the vaccine and the duration of vaccine protection. One study assumed 100% vaccine coverage, 90% vaccine efficacy against HPV 16/18, and lifetime duration of protection. Under these assumptions, an estimated 58% reduction was achieved in the lifetime risk for cervical cancer for the vaccinated cohort.

In a summary of their findings, ACIP suggests routine vaccination of females aged 11-12 years based on several considerations, including studies suggesting that quadrivalent HPV vaccine among adolescents will be safe and effective, high antibody counts achieved after vaccination at age 11-12 years, and the high probability of HPV acquisition within several years of sexual debut.

Regardless of the vaccine debate, there is no argument that HPV presents a mounting threat to the sexually active population in the United States. The virus, so beautifully depicted by animated images and models, remains sinister in its behavior. Stealthy existence in the host, ease of transmission, and fine-tuned virology make it an expert pathogen. Reading articles like this and doing basic research on the internet is a useful way for people to protect themselves, providing a basis from which to cultivate an appreciation and fear of the possible detrimental health effects associated with infection. Getting vaccinated is a proactive way to shield oneself from the growing HPV problem that is sweeping the nation. Hopefully, as HPV’s reputation as a killer spreads and more people begin to protect themselves, it will prevent many needless deaths.       

22 comments:

  1. The two blogs concerning HPV complement each other well. While Kevin McNaught's blog provides a big picture view of how the HPV issue fits into the history and framework of vaccinations, Srdjan Kamenko's blog provides a detailed blow-by-blow description of the the virus, how it is transmitted and what it does. The prevalence of the HPV viruses are truly surprising and their ability to be "silent" or remain undetected for so long make them particularly scary.

    The one figure that I have not seen cited that seems particularly important is the relative proportion of the different virus types within the infected population. In the Javitt et al. (2008) article, the authors state "Many women will never be exposed to the cancer-causing strains of HPV; indeed the prevalence of these strains in the U.S. is quite low." If this is the case, while the percent of the population infected by HPVs may be quite high, if the percent of cancer-causing HPVs within this infected population is low, then the high infection rate, in general, may not be that meaningful. It is hard to assess the true threat and how "scary" these viruses are without these critical figures.

    ReplyDelete
    Replies
    1. Am Laura Mildred by name, i was diagnosed with Herpes 4 years ago i lived in pain with the knowledge that i wasn't going to ever be well again i contacted so many herbal doctors on this issue and wasted a large sum of money but my condition never got better i was determined to get my life back so one day i saw Mr. Morrison Hansen post on how Dr. Emu saved him from Herpes with herbal medicine i contacted Dr. Emu on his Email: Emutemple@gmail.com we spoke on the issue i told him all that i went through and he told me not to worry that everything will be fine again so he prepared the medicine and send it to me and told me how to use it, after 14 days of usage I went to see the doctor for test,then the result was negative, am the happiest woman on earth now thanks to Dr. Emu God bless you. Email him at: Emutemple@gmail.com Call or Whats-app him: +2347012841542

      Delete
    2. God has sent Dr Noah to help people out from this horrible virus. I was diagnosed with HPV for 3 years, a few months ago a friend introduced me to Dr Noah and I only took his natural treatment for 14 days, and I totally got cured with his herbal treatment. If you are suffering from hpv, you don't have to be roaming round Dr Noah email is been attached to contact him on email: dr.noahmedicalcenter@gmail.com CallWhatsApp +1 (310) 982-4670
       Visit website: https://noahmedicalcentre.webs.com/                      https://sites.google.com/view/drnoah/
























































































































      God has sent Dr Noah to help people out from this horrible virus. I was diagnosed with HPV for 3 years, a few months ago a friend introduced me to Dr Noah and I only took his natural treatment for 14 days, and I totally got cured with his herbal treatment. If you are suffering from hpv, you don't have to be roaming round Dr Noah email is been attached to contact him on email: dr.noahmedicalcenter@gmail.com CallWhatsApp +1 (310) 982-4670
       Visit website: https://noahmedicalcentre.webs.com/                      https://sites.google.com/view/drnoah/

      Delete
    3. Truly nature can heal it all. I can conveniently say this because I have walked down that road, I have been between the devil and the deep blue sea, I have seen the bad and the ugly in trying to get my life fixed not withstanding how many times I failed i was still determined to get healing because I was young and had dependants. Physicians told me to learn to leave with itching, pains and burnings and continue to take my pills even when they make me depressed. I decided to exploit more by stuffing the internet and researches behold i read a great testimonies of Dr. White DRWHITETHEHIVHEALER@GMAIL.COM Published by a sincere survival on national daily. Being a herbalist with a big heart the man I will always call dad and savior, we discussed and he vowed to saved me provided I tell others about him after which he sent me the cure through courier to be used twice daily for 2weeks. My only difficulty was one of the medicines was pretty bitter but Don’t just give up hopes now, keep faith, this man is anointed by the most high to help end your HERPES, other VIRUSES and BACTERIAL infections. Email him today or Watsapp +2349091844595 and thank heaven thereafter. Go through the tunnel it promises to give light at the end. For further guidance write me on (phynmarcel15@gmail.com)

      Delete
  2. 5 years ago I had warts, I was treated with some liquid applied to the warts they continued to grow and spread... The next 2 doctors did laser surgery to remove them. 1 year after the surgery, they grew back close to where the 1st ones were' so I was finally told it was hpv. I have had it for very long time, I contract it from my cheated boyfriend and I found out he was also infected and I end up the relationship between us. the warts was so embarrasses because it started spreading all over I have be dealing with this things for very long time the last treatment I take was About 2 years ago I applied natural treatment from Dr onokun herbal cure, a week after applying the treatment all the warts was gone. it's now 2 years and some months I don't have single wart or any symptoms of hpv. wow"" it's great, Dr onokun has finally cured me. Anyone living with hpv contact Dr onokun for natural treatment.
    His email address: dronokunherbalcure@gmail.com  

    ReplyDelete
    Replies
    1. This is real take it serious, i am judith johnson, i am from Ireland. Who will believe that a herbal medicine can cure herpes, I never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for death to come because i was broke, one day i heard about this great man called Dr ODUWA who is well known for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and, he gave my details to the Courier Office. they told me that 4-8 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a checkup, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son and i thought it was a joke, i went to other hospital and was also negative, thank you for saving our life's, I promise I will always testify of your good works. If you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.oduwaspellhome@gmail.com or whatsapp him at +2348070685053.
      THESE ARE THE THINGS Dr ODUWA CURE
      . COLD SORE
      . HIV/AIDS
      . CANCER
      . HPV
      . LASSA FEVER
      . GONORRHEA

      Delete
  3. I Want To Appreciate Dr.OYAGU for his great deeds, I Was Diagnosed With type 2 Herpes Virus Last year,And i Was Looking For Solution To Be Cured Luckily I Saw Testimonies On How Dr.OYAGU Cure Herpes Virus I Decided To Contact Dr.OYAGU I Contacted Him He Prepared A Herbal Medicine Portion And Sent It To Me,I Started The Herbal Medicine For My Health.He Gave Me Step By Step Instructions On How To Apply It, When I Applied It As Instructed, I Was Cured Of This Deadly Herpes Within 2 weeks, I Am Now Herpes Negative.My Brother And Sister I No That There Are So Many People That Have The Same Herpes Virus Please contact Dr OYAGU To Help You Too,And Help Me To Thank Dr.OYAGU For Cure Me, I’m Cured By Dr. OYAGU Herbal Medicine,His Contact Email:oyaguherbalhome@gmail.com

    Or Cell Whatsapp Number +2348101755322 thank you

    ReplyDelete
    Replies
    1. This is real take it serious, i am judith johnson, i am from Ireland. Who will believe that a herbal medicine can cure herpes, I never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for death to come because i was broke, one day i heard about this great man called Dr ODUWA who is well known for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and, he gave my details to the Courier Office. they told me that 4-8 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a checkup, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son and i thought it was a joke, i went to other hospital and was also negative, thank you for saving our life's, I promise I will always testify of your good works. If you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.oduwaspellhome@gmail.com or whatsapp him at +2348070685053.
      THESE ARE THE THINGS Dr ODUWA CURE
      . COLD SORE
      . HIV/AIDS
      . CANCER
      . HPV
      . LASSA FEVER
      . GONORRHEA

      Delete
  4. I Want To Appreciate Dr.OYAGU for his great deeds, I Was Diagnosed With type 2 Herpes Virus Last year,And i Was Looking For Solution To Be Cured Luckily I Saw Testimonies On How Dr.OYAGU Cure Herpes Virus I Decided To Contact Dr.OYAGU I Contacted Him He Prepared A Herbal Medicine Portion And Sent It To Me,I Started The Herbal Medicine For My Health.He Gave Me Step By Step Instructions On How To Apply It, When I Applied It As Instructed, I Was Cured Of This Deadly Herpes Within 2 weeks, I Am Now Herpes Negative.My Brother And Sister I No That There Are So Many People That Have The Same Herpes Virus Please contact Dr OYAGU To Help You Too,And Help Me To Thank Dr.OYAGU For Cure Me, I’m Cured By Dr. OYAGU Herbal Medicine,His Contact Email:oyaguherbalhome@gmail.com

    Or Cell Whatsapp Number +2348101755322 thank you

    ReplyDelete
  5. Greatest thanks to Dr Oyagu for his herbal drugs that he prepared for me and when i start using it in just 2weeks i was completely cured and that ended my HERPES SIMPLEX 1&2 DISEASE i am so happy and grateful to Dr Oyagu . after reading about him on a testimony of Jason Cash on a blogger. i knew suddenly Dr Oyagu was the right Doctor to cure my HERPES SIMPLEX 1&2 DISEASE. i discuss with Dr Oyagu and he prepared a herbal medicine for me and when it got sent to me in south korean . i used the herbal medicine and 2weeks and i went to check up again. after 15years of suffering from HERPES SIMPLEX 1&2 at last i am smiling once again. Dr Oyagu also has remedy to others disease like COLD SORES,HIV/AIDS,DIABETES.CANCER,HIGH BLOOD PRESSURE AND MANY MORE. I oblige everyone to contact this powerful herbalist Dr Oyagu and be free from your suffering. contact his WhatsApp line: +2348101755322 or his Email:Oyaguherbalhome@gmail.com

    ReplyDelete
  6. Hello! I'm very excited to inform everyone that I'm completely cured from my HSV 1&2 recently. I have used Oregano oil, Coconut oil, Acyclovir, Valacyclovir, Famciclovir, and some other products and it's really help during my outbreaks but I totally got cured! from my HSV with a strong and active herbal medicine ordered from a powerful herbalist and it completely fought the virus from my nervous system and I was tested negative after 12 days of using the herbal medicine. I'm here to let y'all know that herpes virus has a complete cure, I got rid of mine with the help of Dr Oyagu and his herbal exploit. Contact him via email: oyaguherbalhome@gmail.com call or whatsApp him on +2348101755322.

    ReplyDelete
    Replies
    1. This is real take it serious, i am judith johnson, i am from Ireland. Who will believe that a herbal medicine can cure herpes, I never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for death to come because i was broke, one day i heard about this great man called Dr ODUWA who is well known for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and, he gave my details to the Courier Office. they told me that 4-8 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a checkup, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son and i thought it was a joke, i went to other hospital and was also negative, thank you for saving our life's, I promise I will always testify of your good works. If you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.oduwaspellhome@gmail.com or whatsapp him at +2348070685053.
      THESE ARE THE THINGS Dr ODUWA CURE
      . COLD SORE
      . HIV/AIDS
      . CANCER
      . HPV
      . LASSA FEVER
      . GONORRHEA

      Delete
  7. Live Testimony HPV and HERPES is cureable: I am greatful to Dr Aire ,the powerful herbal healer that rescue me from HPV and HERPES. I was diagnosed of these disease in 2019 and because of this, i was very unhappy with my life and i went into research on how i can get cured and i saw a testimony of a lady on how she was cured from HERPES by Dr Aire, i decided to give him a try and when i contact him, he assure me that he will help me and send me the cure.I believed in him because all i wanted was to be cured, so he prepared a herbal cure for me and send it to me through DHL and gave me instructions on how to use it and after one week i should go to hospital for checkup and after one week of using the herbal medicine, i went to the hospital for test and to my surprise the test stated that i am HPV and HERPES negative and i am fully cured from the diseases. This gladdens my heart and everybody in the hospital was surprised even the Medical Doctor, So viewers Dr Aire is a God Gifted man and he can cure so many diseases like HIV/AIDS, HERPES,CANCER of all kind, PILE, KIDNEY PROBLEM, SYPHILIS, DIABETES, HSV1&2, HPV and lot's more. You can contact him through his email: drairehome@gmail.com or call and whatsapp him on +2347036740271. I will continue to share this great testimony on the internet and all over the world for the good job Dr Aire has done for me.  

    ReplyDelete
  8. I was diagnosed of herpes virus, I have tried all possible means to get cure but all my effort proved abortive, until a friend of mine introduced me to a herbal doctor called Dr Agaba, who prepare herbal medicine to cure all kind of diseases including herpes virus (Herpes), when i contacted this herbal doctor via email, he sent me herpes virus herbal medicine via courier service, when i received the herbal medicine he gave me step by step instructions on how to apply it, when i applied it as instructed i was totally cured from the virus within 3 weeks of usage. Contact this great herbal doctor today to get your cure. 
    Via Email: Dragabasolutionhome@gmail.com or WhatApp: +2349074536486

    ReplyDelete
  9. Happiness is all i see now I never thought that I will be cured from HERPES virus again. I have been suffering from a deadly disease (HERPES) for the past 3 years now, I had spent a lot of money going from one places to another, from churches to churches, hospitals have been my home every day residence. Constant checks up have been my hobby not until this faithful day, I was searching through the internet, I saw a testimony on how DR agaba helped someone in curing his HERPES disease, quickly I copied his email which is Dragabasolutionhome@gmail.com just to give him a test I spoke to him, he asked me to do some certain things which I did, he told me that he is going to provide the herbal cure to me, which he did, then he asked me to go for medical checkup after some days after using the herbal cure, behold I was free from the deadly disease, he only asked me to post the testimony through the whole world, faithfully am doing it now, please brothers and sisters, he is great, I owe him in return. if you are having a similar problem just email him on : Dragabasolutionhome@gmail.com or WhatApp: +2349074536486  

    ReplyDelete
  10. This is real take it serious, i am judith johnson, i am from Ireland. Who will believe that a herbal medicine can cure herpes, I never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for death to come because i was broke, one day i heard about this great man called Dr ODUWA who is well known for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and, he gave my details to the Courier Office. they told me that 4-8 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a checkup, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son and i thought it was a joke, i went to other hospital and was also negative, thank you for saving our life's, I promise I will always testify of your good works. If you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.oduwaspellhome@gmail.com or whatsapp him at +2348070685053.
    THESE ARE THE THINGS Dr ODUWA CURE
    . COLD SORE
    . HIV/AIDS
    . CANCER
    . HPV
    . LASSA FEVER
    . GONORRHEA

    ReplyDelete
  11. This is real take it serious, i am judith johnson, i am from Ireland. Who will believe that a herbal medicine can cure herpes, I never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for death to come because i was broke, one day i heard about this great man called Dr ODUWA who is well known for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and, he gave my details to the Courier Office. they told me that 4-8 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a checkup, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son and i thought it was a joke, i went to other hospital and was also negative, thank you for saving our life's, I promise I will always testify of your good works. If you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.oduwaspellhome@gmail.com or whatsapp him at +2348070685053.
    THESE ARE THE THINGS Dr ODUWA CURE
    . COLD SORE
    . HIV/AIDS
    . CANCER
    . HPV
    . LASSA FEVER
    . GONORRHEA

    ReplyDelete
  12. This is real take it serious, i am judith johnson, i am from Ireland. Who will believe that a herbal medicine can cure herpes, I never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for death to come because i was broke, one day i heard about this great man called Dr ODUWA who is well known for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and, he gave my details to the Courier Office. they told me that 4-8 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a checkup, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son and i thought it was a joke, i went to other hospital and was also negative, thank you for saving our life's, I promise I will always testify of your good works. If you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.oduwaspellhome@gmail.com or whatsapp him at +2348070685053.
    THESE ARE THE THINGS Dr ODUWA CURE
    . COLD SORE
    . HIV/AIDS
    . CANCER
    . HPV
    . LASSA FEVER
    . GONORRHEA

    ReplyDelete
  13. This is real take it serious, i am judith johnson, i am from Ireland. Who will believe that a herbal medicine can cure herpes, I never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for death to come because i was broke, one day i heard about this great man called Dr ODUWA who is well known for Herpes, HIV, and Cancer cure, i decided to email him I didn't believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine (CURE) and, he gave my details to the Courier Office. they told me that 4-8 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a checkup, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son and i thought it was a joke, i went to other hospital and was also negative, thank you for saving our life's, I promise I will always testify of your good works. If you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via: dr.oduwaspellhome@gmail.com or whatsapp him at +2348070685053.
    THESE ARE THE THINGS Dr ODUWA CURE
    . COLD SORE
    . HIV/AIDS
    . CANCER
    . HPV
    . LASSA FEVER
    . GONORRHEA

    ReplyDelete
  14. I'm 39 years old female I tested genital herpes (HSV1-2) positive in 2002. I was having bad outbreaks. EXTREMELY PAINFUL. I have try different kinds of drugs and treatment by the medical doctors all to know was avail. Six months ago I was desperately online searching for a helpful remedies for genital herpes (HSV1-2) cure, which i come across some helpful remedies on how Dr Oduwa have help so many people in curing genital herpes (HSV1-2) with the help of herbal treatment because I too believe there is someone somewhere in the world who can cure herpes completely. As of the past 2 months, however, I've been following his herpes protocol Via dr.oduwaspellhome@gmail.com and it stopped all outbreaks completely! To my greatest surprise I was cured completely by following the protocol of his herbal medicine . Don't be discouraged by the medical doctors. There is a cure for HSV with the help of herbs and roots kindly contact him for more information Via droduwaspellhome@outlook.com or Whatsapp him on +2348070685053

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  15. It’s a miracle that I am alive today. I encounter herpes virus for good four (4) years, six (6) months and twelve (12) day with my calculations, before I meet the great Dr. ODUWA. I am LEOKADIA STELLA Fresno California, united state of America and I was affected with herpes virus. Herpes is a viral infection cause by the Herpes simplex virus, marked by painful, watery blister in the skin or mucous membrane or on the genitals. This was what I suffered for good four years. I have visited CVS Pharmacy in Fresno for treatment but no improvement. I meet Dr. ODUWA online while I was searching for herpes cure I read a testimony about his work. I give a try that now becomes a testimony in my life. I contacted Dr. ODUWA via his E-mail (DR.ODUWASPELLHOME@GMAIL .COM) and he did not responds to me in time and I went back to the same testimony for his mobile number and I called him immediately (+2348070685053) and he respond to my call. He welcome me as a daughter and I explain my four years situation to him and he said is done just as I have contacted him and I believed in him. Dr. ODUWA sends me some herbal medication for herpes cure and he gave me instruction on what to do and I obeyed his instruction. Changes started after three days of applying the herbal medication. I went to the same CVS Pharmacy in Fresno for test and i was herpes negative. I do not know how to thanks Dr. ODUWA for saving my life. To God be the Glory, I am living healthy with my family today.

    Indeed, Dr. ODUWA is a great man

    and the only thing he requested from me is to share my Testimony for the world to see for a safe living from herpes viral disease and just as I did.

    God bless Dr. ODUWA for his good work....you can wtasapp him on +2348070685053

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  16. it so amazing on everyone who contracted hpv to know about this 100% natural treatment which i also used to cure hpv out of my body. i'm free from this virus i found about the cure online from an ex hpv patient who also got rid of hpv with same natural treatment. everyone suffering from this virus should also inquire this cure. contact the traditional healer Dr Onokun. through his page https://www.facebook.com/naturaltreatmentcenter1 or whatsApp +1 208 425 7799

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